Abstract: Common carp（ Cyprinus carpio） weighing （60 ± 5） g were fed diets containing 10% fish oil oxidized with four peroxide values of 3.6, 69.5, 145.3 and 263.6 mEq O2/kg oil to evaluate pathological changes in the carp fed oxidized fish oil. The 16 - week feeding trial showed that the morbidities and mortalities in the fish fed the diets with peroxide values of 3.6, 69.5, 145.3 and 263.6 mEq O2/kg oil were 0, 16.7%, 40.0%, 76.7% and 0, 10.0%, 23.3%, 40.0%, respectively. Fish fed diets containing oxidized fish oil exhibited poor growth, high mortality, low lateral muscle and high incidence of exudates. Necropsy showed muscle atrophy, tumefaction in both liver and kidney. Focal necrosis was observed in the liver with bluish in color. Red muscle fiber in the lateral body was discolored and its texture turned obscure. Histological observation showed vacuolation and coagulation or lytic focal necrosis in liver tissue; acinus atrophy, degeneration, and necrosis appeared in pancreas tissue. The atrophy, degeneration and necrosis were significantly in the muscle fibers. Ultrastructurely, there were swollen, and disorganization in mitochondria of cardiac muscle fiber and hepatocyte. The intermembranous space of cardiac muscle was enlarged and the intercalated disk was indistinct or extinct. The microvilli were sheded off from renal tubular epithelial cell and the lysosome in renal tubular epithelial cell increased.
叶仕根, 汪开毓, 何显荣. 鲤摄食含氧化鱼油的饲料后其病理学的变化[J]. 大连海洋大学学报, 2006, 21(1): 1-6.
YE Shi-geng, WANG Kai-yu, HE Xian-rong. Pathological changes in Common carp Cyprinus carpio fed oxidized fish oil. Journal of Dalian Ocean University, 2006, 21(1): 1-6.
2006, Vol. 21 
