Effects of sodium butyrate on growth, physico-chemical indices and intestinal structure of common carp Cyprinus carpiofed high dietary levels of carbohydrate or lipid
ZHANG Yuanyuan, Lü Shuo, LU Zhengyi, CUI Pei, SUN Jinhui, QIAO Xiuting, CHENG Zhenyan*
College of Fisheries,Tianjin Key Laboratory of Aquatic Ecology and Aquaculture, Tianjin Agricultural University, Tianjin 300392, China
Abstract: A feeding trail was conducted to investigate the effects of sodium butyrate on growth and health of common carp Cyprinuscarpio fed high dietary levels of carbohydrate or lipid. Common carp with initial body weight of (44.74±0.34)g were reared in an indoor recirculating culture system (80 cm×60 cm×50 cm) and fed basic diet (control group, group D0), containing 7.5% dextrin (high-sugar group, HCD, group D1), containing 10% lipid (high-lipid group, HLD, group D2), basic diet+0.5% sodium butyrate (group SB, group D3 ), high sugar group+0.5% sodium butyrate (group D4) and the high lipid group+0.5% sodium butyrate (group D5) at water temperature of 26.5 ℃ to 30.5 ℃ for 70 d. Then, the growth performance, physico-chemical indices and intestinal structure of common carp were analyzed. The results showed that the common carp fed diets with high levels of carbohydrate or lipid had poor growth performance compared with the control group, without significant difference (P>0.05). The growth of common carp was affected significantly by addition of sodium butyrate. There were significantly higher final body weight, weight gain rate and specific growth rate in the common carp fed the diets containing sodium butyrate than those in the common carp in the control group, increasing by 11.28%, 25.48% and 14.89%, respectively, and the feed conversion ratio was significantly reduced by 8.72% (P<0.05). The feed conversion rate and the body lipid content was shown to be significantly higher in fish fed diets containing high level of lipid than those in other groups (P<0.05), however, the addition of sodium butyrate did not significantly affected the body lipid (P>0.05). Compared with the control group, the contents of serum glucose (GLU) and serum total cholesterol (T-CHO) were increased significantly after feeding high levels of carbohydrate, however, serum GLU and TG decreased significantly while serum T-CHO increased significantly after adding sodium butyrate (P<0.05). The activities of serum catalase (CAT) and total superoxide dismutase (SOD) were found to be increased significantly by 24.45% and 18.96% (P<0.05), and the content of serum malondialdehyde (MDA) was decreased significantly by 13.53% after supplemented with sodium butyrate (P<0.05). High dietary levels of carbohydrate or lipid led to significantly increase in the length of hindgut villi compared with the control group (P<0.05). The length of anterior, middle and posterior intestinal villi was increased significantly in the fish fed diets with sodium butyrate by 19.51%, 27.68% and 26.59%, respectively, compared to those in the control group (P<0.05). In conclusion, the addition of sodium butyrate to diets with high levels of carbohydrate and lipid can lead to improve the growth performance of common carp, which showed positive impact on the physical and chemical indices of serum and intestinal structure.
张媛媛, 吕硕, 卢正义, 崔培, 孙金辉, 乔秀亭, 程镇燕. 高糖、高脂饲料中添加丁酸钠对鲤生长、生化指标和肠道结构的影响[J]. 大连海洋大学学报, 2022, 37(5): 747-755.
ZHANG Yuanyuan, Lü Shuo, LU Zhengyi, CUI Pei, SUN Jinhui, QIAO Xiuting, CHENG Zhenyan. Effects of sodium butyrate on growth, physico-chemical indices and intestinal structure of common carp Cyprinus carpiofed high dietary levels of carbohydrate or lipid. Journal of Dalian Ocean University, 2022, 37(5): 747-755.
2022, Vol. 37 
