Abstract: Small GTPases (containing more than 100 members) as a large superfamily in eukaryotic cells can be classified into five subfamilies (Ras， Rho， Rab， Ran and Arf) according to their sequence characterization and bio-functions and play vital roles in various physiological processes of organisms, including cell differentiation, growth and development, and tumorigenesis, especially in cell differentiation, cytoskeleton development and innate immune responses in marine animals. In this study, we reviewed the recent advances on the research of small GTPase family members in marine organisms, including species composition, functions and mechanisms to provide more information and data for further understanding of the gene sequence, evolutionary characteristics and biological functions of members in the small GTPase family in marine organisms.
2019, Vol. 34 
