Research progress on molecular regulation mechanism of skin ulcer syndrome in sea cucumber Apostichopus japonicus:a review
LI Chenghua1,2
1.State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Ningbo University, Ningbo 315832, China; 2.Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266071, China
Abstract: Since 2003, the development speed and scale of the sea cucumber Apostichopusjaponicus industry have reached unprecedented levels, forming the “fifth” wave of marine aquaculture industry in China after kelp, prawns, scallops, and marine fish farming. With the expansion of breeding scale and density, disease problems have become increasingly prominent, and have gradually become a bottleneck for the healthy development of sea cucumber industry, posing a huge threat to the ecological environment and food safety, among which the skin ulcer syndrome (SUS) is the most representative. The main pathogens of sea cucumber suffered from SUS, systematical immune regulation mechanism of sea cucumber against pathogen infection, the research progress of representative pathogenic mechanisms and ecological control methods of sea cucumber diseases are discussed in detail. Corresponding development countermeasures are proposed for the healthy and sustainable development of the sea cucumber industry, the pathogenic mechanism of pathogens and the research on the occurrence of environmental control diseases in order to provide reference with the construction of green and healthy sea cucumber disease prevention and control strategies.