Progress on breeding of disease-resistant fishes：a review
ZHOU Xin1,2, GAO Fengying1, LU Maixin1*
1.Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation, Ministry of Agriculture and Rural Affairs, Pearl River Fisheries Research Institute，Chinese Academy of Fishery Sciences, Guangzhou 510380, China; 2.College of Fisheries and Life Sciences, Shanghai Ocean University, Shanghai 201306, China
Abstract: Cultivating excellent disease-resistant fish varieties can effectively solve and reduce more and more serious disease problems with the transformation of aquaculture mode from extensive to intensive. The development of fish disease-resistant breeding is primarily summarized, including the research progress of family and population breeding, molecular marker-assisted breeding, genomic selection and major histocompatibilty complex (MHC) gene polymorphism and disease resistance. Family and population breeding, one of the important means of selective breeding, has been widely used in a variety of fish disease-resistant breeding research. The introduction of molecular marker-assisted breeding and genomic selection has also promoted the progress of disease-resistant breeding in the aquaculture industry. In addition, the high polymorphism of the fish MHC gene associated with disease-resistant phenotype has made it a candidate for disease-resistant breeding molecule markers. The problems and shortcomings in the breeding of disease-resistant fish and the prospect of disease-resistant breeding of fish are discussed in the future, aiming to provide reference with the green and healthy development of the aquaculture industry.
2021, Vol. 36 
