Research progress on diseases caused by pathogen Streptococcus parauberis in fish: a review
LI Zhanjun, ZHANG Jianbai, CAO Ya’nan, CHEN Kun, LIU Peng, XU Huizhang, WANG He
1.Shandong Fisheries Development and Resources Conservation Center, Yantai 264003, China; 2.Yantai Marine Economic Research Institute, Yantai 264006, China
Abstract: Streptococcusparauberis as the main pathogen of streptococcosis in cattle and fish has brought huge economic losses due to strong contagiousness and wide distribution. It was originally considered to be S.uberis type Ⅱ and then identified as a new specie by molecular identification. The bacterium can infect many fishes, which caused clinical symptoms with characteristics of suppurative exophalmia and meningoencephalitis. Temperature was the most important cause of disease in its epidemic outbreak. According to the structural differences in capsular polysaccharides, it can divides into several serotypes showing various virulence to the host. Conventional physiological-biochemical identification method is difficult to identify S.parauberis accurately, thus molecular identification is the most common way based on PCR technology. At present, aquaculture depends on antibiotics to treat or prevent S.parauberis disease in fish. But there appear antimicrobials-resistant strains or even multi-drug-resistant strains. Vaccination is an alternative method to control streptococcal diseases though vaccination needs to be further tested. There is a tendency that bacteriophage may become a substitute for antibiotic drugs. This paper summarizes the research progress on etiology, epidemiology and clinical symptoms, pathogenic mechanism, detection methods, drug resistance and prevention measures in order to provide effective means of prevention and control of S.parauberis in fish.
李战军, 张建柏, 曹亚男, 陈坤, 刘蓬, 徐惠章, 王鹤. 鱼类副乳房链球菌病研究进展[J]. 大连海洋大学学报, 2021, 36(6): 1059-1070.
LI Zhanjun, ZHANG Jianbai, CAO Ya’nan, CHEN Kun, LIU Peng, XU Huizhang, WANG He. Research progress on diseases caused by pathogen Streptococcus parauberis in fish: a review. Journal of Dalian Ocean University, 2021, 36(6): 1059-1070.
2021, Vol. 36 
