Abstract: Alga polyphenols,as secondary metabolites of algae,protect algae against herbivorous animal interference,and have a variety of biological activities,becoming a hot research direction of marine bioactive substances. The development of extraction methods and purification techniques are overviewed,and the mechanism of bioactivities of alga polyphenols are described including antioxidation,antibacterial,antiviral,antitumor,anti allergic,anti inflammatory,anticoagulation,glucose homeostasis and other biological activities.The relationships between chemical structure and biological activity and the application status of polyphenols are presented simultaneously.Therefore,alga polyphenols has sustainable utilizing value.The further research is needed on the functional structures, mechanism of biological activity,and application of alga polyphenols to develop great potential of alga polyphenols in industrial and agricultural production.