Abstract: Plantigrades of thick shell mussel Mytilus coruscus with shell length of(1.31±0.05)mm were fed algae Isochrysis zhanjiangensis,and Platymonas helgolandica var.tsingtaoensis,and a mixture of the two algae at volumetric proportion of 1∶1 at water temperature of 18℃and a salinity of 30 for 21 days,and survival rate,shell length,shell height,wet body weight,specific growth rate(SGR)and amylase activity of the plantigrades were determined in order to understand the effects of different diets on the growth,survival and digestion of thick shell mussel juveniles.The results showed that there were no significant differences in survival rates(over 93%)in all groups(P>0.05).However,the plantigrades fed the mixture of the two algae had significantly higher SGR,and amylase activity than the animals fed single alga did during over 14 day rearing period(P<0.05).The findings will provide an important theoretical basis for the cultivation of thick shell mussel plantigrades.