Abstract: A 30 day feeding trial was conducted to investigate the effects of dietary fish meal replaced by Hermetia illucens meal on growth performance,body composition and plasma biochemical indices of koi carp Cyprinus carpio. A total of 270 individuals with an average body weight of 51.2 g were randomly assigned into 3 groups with 3 replicates per group and 30 fish per replicate and fed three diets containing 0(H1),50%(H2),and 70%(H3)of fish meal replaced by Hermetia illucens meal on basal diet basis.The results showed that there was no significant difference in weight gain rate,condition factor,hepatosomatic index,and shape among all groups(P>0.05).Glutamic-pyruvic transaminase(GPT)and glutamic-oxalacetic transaminase(GOT)activities were significantly inhibited in plasma of the koi carp fed the diets containing high Hermetia illucens meal(P<0.05),with high GOT activity in the fish fed the diet containing 70%fish meal replaced by Hermetia illucens meal.There was significantly higher activity of superoxide dismutase(SOD)in plasma and hepatopancreas in groups H2 and H3 than that in the control group(P<0.05).However,the koi in groups H2 and H3 had significantly lower malondialdehyde(MDA) content in hepatopancreas than the fish in the control group did(P<0.05).The findings indicate that Hermetia illucens meal leads to improve oxidation resistance and disease resistance in koi carp,and suggeste that fish meal replaced by maggot meal should not be more than 70%in diets.