Abstract Molluscs play an important role in mariculture industry. In recent years, the frequent occurrence of molluscan diseases has seriously hindered the sustainable and healthy development of molluscan aquaculture industry. Inflammation is a kind of defense response of the body to stimuli, which plays an important role in resisting against pathogen infection. But the excessive inflammatory response can cause tissue damage and, in severe cases, death. Recently, more and more studies have found the presence of inflammation in molluscs and identified a variety of inflammatory factors and inflammatory-related signaling pathways. This paper summarizes the current progress of molluscan inflammation and emphasizes the molecular mechanism of inflammation in recent years by focusing on the types and biological functions of inflammatory factors, inflammatory-related signaling pathways and morphological characteristics of inflammatory responses. At the same time, in view of the problems existing in the current research, it is proposed that the exploration of different types of inflammatory factors, the immune functions of inflammatory factors and its relation to different types of immune cells remains significantly concern in the future research, aiming to provide references for promoting the green and high-quality development of molluscan aquaculture industry.
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Published: 12 July 2023
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