Journal of Dalian Ocean University  2023, Vol. 38 Issue (4): 726- DOI: 10.16535/j.cnki.dlhyxb.2022-293 |
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| Advances in effects and regulatory mechanism of cortisol on process of sex differentiation in fish: a review |
| GAO Rui，YAN Hongwei*，LIU Ying，LIU Qi
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| 1.College of Marine Science and Environment，Dalian Ocean University，Dalian 116023，China；2.Key Laboratory of Environment Controlled Aquaculture (Dalian Ocean University)，Dalian 116023，China；3.The Key Laboratory of Pufferfish Breeding and Culture in Liaoning Province，Dalian 116023，China；4.College of Biosystems Engineering and Food Science，Zhejiang University，Hangzhou 310058，China |
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Abstract Sex determination and differentiation of fish has been increasingly concerned in the fields of developmental biology, reproductive physiology, and genetics and breeding in recent years. Unlike other vertebrates, sex determination and differentiation of fish are featured by high plasticity, and is influenced by several environmental factors such as temperature, density, and pH. Exploration of the molecular mechanism of sex determination and differentiation of fish is crucially important for sex control breeding, and conducive to improving aquaculture efficiency. Recently, is proved cortisol, the predominant glucocorticoid in fish, has an important role in the process of sex differentiation in fish. The effects of exogenous cortisol treatment on fish sex differentiation, the effects of environmental factors on the variation pattern of endogenous cortisol levels during fish sex differentiation and sex change, and the molecular mechanism of cortisol in regulating sex differentiation and sex change are summarized. Some suggestions for future research are proposed including understanding of the mechanism of cortisol-induced masculinization and the interaction of cortisol and epigenetic factors, aiming to provide theoretical reference for further exploring the functional and regulatory roles of cortisol.
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Published: 06 November 2023
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