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大连海洋大学学报  2020, Vol. 35 Issue (5): 755-761    DOI: 10.16535/j.cnki.dlhyxb.2019-149
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嗜冷黄杆菌及细菌性冷水病的研究进展
柴静茹1、2、3,王荻1、2,卢彤岩1、2,曹永生1、2,刘红柏1、2,李绍戊1、2*
1.中国水产科学研究院黑龙江水产研究所,黑龙江 哈尔滨 150070; 2. 黑龙江省水生动物病害与免疫重点实验室, 黑龙江 哈尔滨 150070; 3.上海海洋大学 水产科学国家级实验教学示范中心,上海 201306
Research progress on Flavobacterium psychrophilum and bacterial coldwater disease: a review
CHAI Jingru1,2,3, WANG Di1,2, LU Tongyan1,2, CAO Yongsheng1,2, LIU Hongbai1,2, LI Shaowu1,2*
1.Heilongjiang River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, China; 2.Key Laboratory of Aquatic Animal Diseases and Immune Technology of Heilongjiang Province, Harbin 150070, China; 3.National Demonstration Center for Experimental Fisheries Science Education, Shanghai Ocean University, Shanghai 201306, China
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摘要 嗜冷黄杆菌Flavobacterium psychrophilum是细菌性冷水病(Bacterial cold water disease,BCWD)或虹鳟鱼苗综合征(Rainbow trout fry syndrome, RTFS)的病原,主要感染鲑科鱼类幼鱼并可导致较高的死亡率,该菌地理分布广泛,亦可感染非鲑科鱼类并造成疾病。BCWD又称低温病,通常在3~15 ℃时发生流行,其典型的临床症状包括尾柄部腐蚀、皮肤溃疡、鳃苍白、脾肿大、腹水和螺旋式游泳行为等。目前,对嗜冷黄杆菌及BCWD的研究主要集中在遗传多样性、耐药性、致病性和免疫防控等方面,而关于嗜冷黄杆菌的致病机制仍不够清晰。本文综述了嗜冷黄杆菌的分类地位、生物学性状、致病机制,以及BCWD的流行病学和防控技术,以期为BCWD的防控提供科学参考。
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柴静茹、、
王荻、
卢彤岩、
曹永生、
刘红柏、
李绍戊、
关键词:  嗜冷黄杆菌  细菌性冷水病  致病性  流行病学  防控技术    
Abstract: Flavobacterium psychrophilum as a causative agent of bacterial coldwater disease (BCWD) and rainbow trout fry syndrome (RTFS) mainly infects juvenile salmonids, with high level of mortality and huge economic losses in salmonid aquaculture worldwide. F.psychrophilum is characterized by a broad geographical distribution and prevalence of disease in non-salmonid fishes including low temperature disease usually found at water temperature of 3-15 ℃, with the typical clinical signs of caudal peduncle erosion, skin ulcerations, pale gills, enlarged spleen, ascites and spiral swimming behavior. At present, research on F.psychrophilum and BCWD mainly focuses on the genetic diversity, antimicrobial susceptibility, pathogenicity, immunization and prevention. However, the pathogenisis of F.psychrophilum is still unclear. This paper reviews the taxonomic status, biological characteristics and pathogenicity of F.psychrophilum and summarizes the epidemiology, prevention and control techniques of BCWD in order to provide reference for the control of this disease.
Key words:  Flavobacterium psychrophilum    bacterial coldwater disease    pathogenicity    epidemiology    prevention and control technology
               出版日期:  2020-10-12      发布日期:  2020-10-12      期的出版日期:  2020-10-12
中图分类号:  S941.42  
基金资助: 中央级公益性科研院所基本科研业务费专项(HSY201902Q);国家现代农业产业技术体系专项(CARS-46)
引用本文:    
柴静茹, 王荻, 卢彤岩, 曹永生, 刘红柏, 李绍戊. 嗜冷黄杆菌及细菌性冷水病的研究进展[J]. 大连海洋大学学报, 2020, 35(5): 755-761.
CHAI Jingru, WANG Di, LU Tongyan, CAO Yongsheng, LIU Hongbai, LI Shaowu, . Research progress on Flavobacterium psychrophilum and bacterial coldwater disease: a review. Journal of Dalian Ocean University, 2020, 35(5): 755-761.
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https://xuebao.dlou.edu.cn/CN/10.16535/j.cnki.dlhyxb.2019-149  或          https://xuebao.dlou.edu.cn/CN/Y2020/V35/I5/755
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